The cytokine and chemokine profiles in patients with hand, foot and mouth disease of different severities in Shanghai, China, 2010.

• Main Authors: Mei Zeng (Author), Xiaoyan Zheng (Author), Ruicheng Wei (Author), Na Zhang (Author), Kai Zhu (Author), Bin Xu (Author), Chun-Hui Yang (Author), Chun-Fu Yang (Author), Chaoyang Deng (Author), Dongbo Pu (Author), Xiaohong Wang (Author), Ralf Altmeyer (Author), Qibin Leng (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND AND PURPOSE: Systemic upregulation of inflammatory cytokines is characteristic of critical severe hand, foot, and mouth disease (HFMD) with pulmonary edema. Thus, immunomodulatory medicines such as steroids, including methylprednisolone, have been proposed to treat patients with severe HF...