Volume Transmission of Substance P in Striatum Induced by Intraplantar Formalin Injection Attenuates Nociceptive Responses via Activation of the Neurokinin 1 Receptor

• Auteurs principaux: Yoki Nakamura (Auteur), Hiroki Izumi (Auteur), Takumi Shimizu (Auteur), Kazue Hisaoka-Nakashima (Auteur), Norimitsu Morioka (Auteur), Yoshihiro Nakata (Auteur)
• Format: Livre
• Publié: Elsevier, 2013-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Abstract.: To clarify a role of substance P (SP) in an endogenous pain control mechanism involving the rat striatum, striatal SP release was measured over time by microdialysis following intraplantar injection of 0.4% formalin. A slow-onset but significant increase of SP and neurokinin 1 receptor (N...