Fibroid explants reveal a higher sensitivity against MDM2-inhibitor nutlin-3 than matching myometrium

• Main Authors: Markowski Dominique N (Author), Helmke Burkhard M (Author), Radtke Arlo (Author), Froeb Jennifer (Author), Belge Gazanfer (Author), Bartnitzke Sabine (Author), Wosniok Werner (Author), Czybulka-Jachertz Iris (Author), Deichert Ulrich (Author), Bullerdiek Jörn (Author)
• Format: Book
• Published: BMC, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Spontaneous cessation of growth is a frequent finding in uterine fibroids. Increasing evidence suggests an important role of cellular senescence in this growth control. Deciphering the underlying mechanisms of growth control that can...