Nano-bio interfaces effect of two-dimensional nanomaterials and their applications in cancer immunotherapy

The field of two-dimensional (2D) nanomaterial-based cancer immunotherapy combines research from multiple subdisciplines of material science, nano-chemistry, in particular nano-biological interactions, immunology, and medicinal chemistry. Most importantly, the "biological identity" of nano...

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Main Authors: Zhongmin Tang (Author), Yufen Xiao (Author), Na Kong (Author), Chuang Liu (Author), Wei Chen (Author), Xiangang Huang (Author), Daiyun Xu (Author), Jiang Ouyang (Author), Chan Feng (Author), Cong Wang (Author), Junqing Wang (Author), Han Zhang (Author), Wei Tao (Author)
Format: Book
Published: Elsevier, 2021-11-01T00:00:00Z.
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100 1 0 |a Zhongmin Tang  |e author 
700 1 0 |a Yufen Xiao  |e author 
700 1 0 |a Na Kong  |e author 
700 1 0 |a Chuang Liu  |e author 
700 1 0 |a Wei Chen  |e author 
700 1 0 |a Xiangang Huang  |e author 
700 1 0 |a Daiyun Xu  |e author 
700 1 0 |a Jiang Ouyang  |e author 
700 1 0 |a Chan Feng  |e author 
700 1 0 |a Cong Wang  |e author 
700 1 0 |a Junqing Wang  |e author 
700 1 0 |a Han Zhang  |e author 
700 1 0 |a Wei Tao  |e author 
245 0 0 |a Nano-bio interfaces effect of two-dimensional nanomaterials and their applications in cancer immunotherapy 
260 |b Elsevier,   |c 2021-11-01T00:00:00Z. 
500 |a 2211-3835 
500 |a 10.1016/j.apsb.2021.05.004 
520 |a The field of two-dimensional (2D) nanomaterial-based cancer immunotherapy combines research from multiple subdisciplines of material science, nano-chemistry, in particular nano-biological interactions, immunology, and medicinal chemistry. Most importantly, the "biological identity" of nanomaterials governed by bio-molecular corona in terms of bimolecular types, relative abundance, and conformation at the nanomaterial surface is now believed to influence blood circulation time, bio-distribution, immune response, cellular uptake, and intracellular trafficking. A better understanding of nano-bio interactions can improve utilization of 2D nano-architectures for cancer immunotherapy and immunotheranostics, allowing them to be adapted or modified to treat other immune dysregulation syndromes including autoimmune diseases or inflammation, infection, tissue regeneration, and transplantation. The manuscript reviews the biological interactions and immunotherapeutic applications of 2D nanomaterials, including understanding their interactions with biological molecules of the immune system, summarizes and prospects the applications of 2D nanomaterials in cancer immunotherapy. 
546 |a EN 
690 |a Two-dimensional nanomaterials 
690 |a Nano-bio interactions 
690 |a Immune system 
690 |a Antigens 
690 |a Adjuvants 
690 |a Modulators 
690 |a Therapeutics. Pharmacology 
690 |a RM1-950 
655 7 |a article  |2 local 
786 0 |n Acta Pharmaceutica Sinica B, Vol 11, Iss 11, Pp 3447-3464 (2021) 
787 0 |n http://www.sciencedirect.com/science/article/pii/S2211383521001696 
787 0 |n https://doaj.org/toc/2211-3835 
856 4 1 |u https://doaj.org/article/e21c7e3e9f74432e94c634721843f22b  |z Connect to this object online.