The Utilisation Of Thermal Methods For The Screening Of Three Component Co-amorphous Systems

Indomethacin and piroxicam are known to become amorphous upon rapid cooling after melting. Multiple three-component co-amorphous mixtures have been produced via a melt quench method to evaluate the influence of the third component on stability and physical properties on the co-amorphous mixture of p...

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Bibliographic Details
Main Authors: Alessandra D'Angelo (Author), Benjamin Edgar (Author), Milan Antonijevic (Author)
Format: Book
Published: University of Huddersfield Press, 2018-07-01T00:00:00Z.
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100 1 0 |a Alessandra D'Angelo  |e author 
700 1 0 |a Benjamin Edgar  |e author 
700 1 0 |a Milan Antonijevic   |e author 
245 0 0 |a The Utilisation Of Thermal Methods For The Screening Of Three Component Co-amorphous Systems 
260 |b University of Huddersfield Press,   |c 2018-07-01T00:00:00Z. 
500 |a 10.5920/bjpharm.2017.21 
500 |a 2058-8356 
520 |a Indomethacin and piroxicam are known to become amorphous upon rapid cooling after melting. Multiple three-component co-amorphous mixtures have been produced via a melt quench method to evaluate the influence of the third component on stability and physical properties on the co-amorphous mixture of piroxicam and indomethacin. These have then been tested using thermal gravimetric analysis, differential scan calorimetry and hot stage microscopy. Results have confirmed the creation of a three-component co-amorphous system. 
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690 |a co-amorphous 
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690 |a Pharmacy and materia medica 
690 |a RS1-441 
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786 0 |n British Journal of Pharmacy, Vol 2, Iss 2 (2018) 
787 0 |n https://www.bjpharm.org.uk/article/id/50/ 
787 0 |n https://doaj.org/toc/2058-8356 
856 4 1 |u https://doaj.org/article/e22f267f0df24a4e93618d639a2c4ebc  |z Connect to this object online.