A novel hotspot and rare somatic mutation p.A138V, at TP53 is associated with poor survival of pancreatic ductal and periampullary adenocarcinoma patients

• Main Authors: Gourab Saha (Author), Richa Singh (Author), Argha Mandal (Author), Subrata Das (Author), Esita Chattopadhyay (Author), Prasun Panja (Author), Paromita Roy (Author), Navonil DeSarkar (Author), Sumit Gulati (Author), Supriyo Ghatak (Author), Shibajyoti Ghosh (Author), Sudeep Banerjee (Author), Bidyut Roy (Author), Saurabh Ghosh (Author), Dipankar Chaudhuri (Author), Neeraj Arora (Author), Nidhan K. Biswas (Author), Nilabja Sikdar (Author)
• Format: Book
• Published: BMC, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pancreatic Ductal Adenocarcinoma (PDAC) is a cancer of the exocrine pancreas and 5-year survival rates remain constant at 7%. Along with PDAC, Periampullary Adenocarcinoma (PAC) accounts for 0.5-2% of all gastrointestinal malignancies. Genomic observations were well concluded for...