Idiopathic non-familial Acro-osteolysis: A rare case report

A 25-year-old woman patient presented with shortening of fingers with racket nails and numerous yellowish papules over the hands and forearms for 21 years. X-ray of the hands revealed destructive osteolytic changes in all the terminal phalanges. Skin biopsy from the yellowish papules showed epiderma...

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Bibliographic Details
Main Authors: Pijush K Datta (Author), Sanjay Ghosh (Author), Abhishek De (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2012-01-01T00:00:00Z.
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100 1 0 |a Pijush K Datta  |e author 
700 1 0 |a Sanjay Ghosh  |e author 
700 1 0 |a Abhishek De  |e author 
245 0 0 |a Idiopathic non-familial Acro-osteolysis: A rare case report 
260 |b Wolters Kluwer Medknow Publications,   |c 2012-01-01T00:00:00Z. 
500 |a 0019-5154 
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500 |a 10.4103/0019-5154.103071 
520 |a A 25-year-old woman patient presented with shortening of fingers with racket nails and numerous yellowish papules over the hands and forearms for 21 years. X-ray of the hands revealed destructive osteolytic changes in all the terminal phalanges. Skin biopsy from the yellowish papules showed epidermal proliferation, perivascular mononuclear infiltrate, thickening of dermal collagen, septal fibrosis and loss of adipocytes mimicking sclerodermatous changes in the dermis and hypodermis. The patient did not have any history of similar illness in the family or occupational exposure to vinyl chloride. After excluding all other possibilities of acral-osteolysis, we diagnosed the case as idiopathic non-familial variety of acro-osteolysis. This is a rare entity characterized by terminal resorption of fingers, sometimes associated with Raynaud's phenomena and yellowish cutaneous papules. 
546 |a EN 
690 |a Acro-osteolysis 
690 |a idiopathic 
690 |a scleroderma 
690 |a Dermatology 
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786 0 |n Indian Journal of Dermatology, Vol 57, Iss 6, Pp 486-488 (2012) 
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