Expression of BMP and Actin Membrane Bound Inhibitor Is Increased during Terminal Differentiation of MSCs

• Main Authors: Christian G. Pfeifer (Author), Alexandra Karl (Author), Arne Berner (Author), Johannes Zellner (Author), Paul Schmitz (Author), Markus Loibl (Author), Matthias Koch (Author), Peter Angele (Author), Michael Nerlich (Author), Michael B. Mueller (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chondrogenic differentiating mesenchymal stem cells (MSCs) are mimicking embryonal endochondral ossification and become hypertrophic. BMP (bone morphogenetic protein) and Activin Membrane Bound Inhibitor (BAMBI) is a pseudoreceptor that regulates the activity of transforming growth factor-β (TGF-β)...