Benzamide Derivatives Targeting the Cell Division Protein FtsZ: Modifications of the Linker and the Benzodioxane Scaffold and Their Effects on Antimicrobial Activity

• Main Authors: Valentina Straniero (Author), Lorenzo Suigo (Author), Andrea Casiraghi (Author), Victor Sebastián-Pérez (Author), Martina Hrast (Author), Carlo Zanotto (Author), Irena Zdovc (Author), Carlo De Giuli Morghen (Author), Antonia Radaelli (Author), Ermanno Valoti (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Filamentous temperature-sensitive Z (FtsZ) is a prokaryotic protein with an essential role in the bacterial cell division process. It is widely conserved and expressed in both Gram-positive and Gram-negative strains. In the last decade, several research groups have pointed out molecules able to targ...