Cell-free fetal DNA as a non-invasive method using pyrosequencing in detecting beta-globin gene mutation: A pilot study from area with limited facilities in Indonesia

• Κύριοι συγγραφείς: Ani Melani Maskoen (Συγγραφέας), Nurul Setia Rahayu (Συγγραφέας), Bremmy Laksono (Συγγραφέας), Azzania Fibriani (Συγγραφέας), Willyanti Soewondo (Συγγραφέας), Johanes C. Mose (Συγγραφέας), Edhyana Sahiratmadja (Συγγραφέας), Ramdan Panigoro (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

BackgroundThalassemia is a monogenic, autosomal recessive, inherited disorder of the red blood cells caused by mutations or deletions in the globin gene. Approximately 6-10% of the Indonesian population carries the β-globin gene mutation; however, premarital screening is rarely conducted, and antena...