Naturally occurring anti M complicating ABO grouping

Anti M is considered a naturally occurring antibody that is usually active at temperatures below 37°C and is thus of no clinical significance. This antibody, if present in an individual, can lead to a discrepancy between forward and reverse ABO grouping and thus creates diagnostic difficulties for b...

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Bibliographic Details
Main Authors: Safoorah Khalid (Author), Roelyn Dantes (Author), Sunu Varghese (Author), Imadeddin Al Hakawati (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2011-01-01T00:00:00Z.
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Summary:Anti M is considered a naturally occurring antibody that is usually active at temperatures below 37°C and is thus of no clinical significance. This antibody, if present in an individual, can lead to a discrepancy between forward and reverse ABO grouping and thus creates diagnostic difficulties for blood bank staff. We report a case of a 58-year-old lady who had an unexpected reaction in reverse grouping due to anti M that posed a problem for us in the interpretation of results of her blood group. We also reviewed the literature to find out the significance of such discrepancy in blood grouping.
Item Description:0377-4929
10.4103/0377-4929.77394