Oral field cancerization: an update on current concepts

There always exists a field with genetically altered cells with a high risk of developing premalignant and malignant lesions. It may often happen that an individual stem cell is genetically altered and can cause the formation of a clone or a patch which is likely to turn into a tumor. This explains...

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Bibliographic Details
Main Authors: Meenakshi Mohan (Author), Nithya Jagannathan (Author)
Format: Book
Published: Frontiers Media S.A., 2014-06-01T00:00:00Z.
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Summary:There always exists a field with genetically altered cells with a high risk of developing premalignant and malignant lesions. It may often happen that an individual stem cell is genetically altered and can cause the formation of a clone or a patch which is likely to turn into a tumor. This explains the higher recurrence rates following tumor resections. It is essential to identify and to treat this field in order to have greater chances to prevent cancer and achieve a better outcome. This article reports concepts, theories and markers for the assessment of field cancerization.
Item Description:10.4081/oncol.2014.244
1970-5557
1970-5565