Disruption of Cholinergic Circuits as an Area for Targeted Drug Treatment of Alzheimer's Disease: In Vivo Assessment of Short-Term Plasticity in Rat Brain

• Prif Awduron: Vergine Chavushyan (Awdur), Ani Soghomonyan (Awdur), Gohar Karapetyan (Awdur), Karen Simonyan (Awdur), Konstantin Yenkoyan (Awdur)
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• Cyhoeddwyd: MDPI AG, 2020-10-01T00:00:00Z.
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The search for new therapeutics for the treatment of Alzheimer's disease (AD) is still in progress. Aberrant pathways of synaptic transmission in basal forebrain cholinergic neural circuits are thought to be associated with the progression of AD. However, the effect of amyloid-beta (Aβ) on shor...