Direct and Indirect Effects of Crisaborole Ointment on Quality of Life in Patients with Atopic Dermatitis: A Mediation Analysis

• Главные авторы: Eric L. Simpson (Автор), Gil Yosipovitch (Автор), Andrew G. Bushmakin (Автор), Joseph C. Cappelleri (Автор), Thomas Luger (Автор), Sonja Ständer (Автор), Wynnis L. Tom (Автор), William C. Ports (Автор), Michael A. Zielinski (Автор), Anna M. Tallman (Автор), Huaming Tan (Автор), Robert A. Gerber (Автор)
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• Опубликовано: Medical Journals Sweden, 2019-05-01T00:00:00Z.
• Предметы: article
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Crisaborole ointment is a nonsteroidal phosphodiesterase 4 inhibitor for the treatment of mild to moderate atopic dermatitis. Using pooled data from two phase 3 studies (NCT02118766/NCT02118792), mediation modeling determined the interrelationship among pruritus, quality of life (QoL), and treatment...