Effects of polyethylene glycols on intestinal efflux pump expression and activity in Caco-2 cells

The present study was planned to investigate the influence of polyethylene glycols (PEGs) on the activity and expression of P-glycoprotein (P-gp). Sub-toxic concentrations of PEGs in Caco-2 cells were determined using the MTT test assay. Then the measurement of Rhodamine-123 (Rho-123) uptake, a P-gp...

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Bibliographic Details
Main Authors: Darya Hodaei (Author), Behzad Baradaran (Author), Hadi Valizadeh (Author), Parvin Zakeri-Milani (Author)
Format: Book
Published: Universidade de São Paulo, 2015-09-01T00:00:00Z.
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