Intra-tumoral drug concentration mapping within solid tumor micro-milieu using in-vitro model and doxorubicin as a model drug
In contrast to plasma pharmacokinetics, intratumoral pharmacokinetics of doxorubicin (DOX) determines its spatial anti-tumoral activity. Three-dimensional multicellular layers (MCL) model for solid tumors present optimum experimental platform for studying the intratumoral pharmacokinetics of DOX. Th...
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Main Authors: | Ahmed M. Al-Abd (Author), Alaa Khedr (Author), Salah G. Atteiah (Author), Fahad A. Al-Abbasi (Author) |
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Format: | Book |
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Elsevier,
2020-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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