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Binding mode of triazole derivatives as aromatase inhibitors based on docking, protein ligand interaction fingerprinting, and molecular dynamics simulation studies

Aromatase inhibitors (AIs) as effective candidates have been used in the treatment of hormone-dependent breast cancer. In this study, we have proposed 300 structures as potential AIs and filtered them by Lipinski's rule of five using DrugLito software. Subsequently, they were subjected to docki...

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Autors principals:	Ayyub Mojaddami (Autor), Amirhossein Sakhteman (Autor), Masood Fereidoonnezhad (Autor), Zeinab Faghih (Autor), Atena Najdian (Autor), Soghra Khabnadideh (Autor), Hossein Sadeghpour (Autor), Zahra Rezaei (Autor)
Format:	Llibre
Publicat:	Wolters Kluwer Medknow Publications, 2017-01-01T00:00:00Z.
Matèries:	article
Accés en línia:	Connect to this object online.
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