Structural and Bioactivity Characterization of Filipin Derivatives from Engineered <i>Streptomyces filipinensis</i> Strains Reveals Clues for Reduced Haemolytic Action

• Κύριοι συγγραφείς: Eva G. Barreales (Συγγραφέας), Ángel Rumbero (Συγγραφέας), Tamara D. Payero (Συγγραφέας), Antonio de Pedro (Συγγραφέας), Ester Jambrina (Συγγραφέας), Jesús F. Aparicio (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2020-07-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

The rise in the number of immunocompromised patients has led to an increased incidence of fungal infections, with high rates of morbidity and mortality. Furthermore, misuse of antifungals has boosted the number of resistant strains to these agents; thus, there is urgent need for new drugs against th...