β-catenin is selectively required for the expansion and regeneration of mature pancreatic acinar cells in mice

• Hauptverfasser: Matthew D. Keefe (Verfasst von), Hui Wang (Verfasst von), Jean-Paul De La O (Verfasst von), Ameena Khan (Verfasst von), Matthew A. Firpo (Verfasst von), L. Charles Murtaugh (Verfasst von)
• Format: Buch
• Veröffentlicht: The Company of Biologists, 2012-07-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

SUMMARY The size of the pancreas is determined by intrinsic factors, such as the number of progenitor cells, and by extrinsic signals that control the fate and proliferation of those progenitors. Both the exocrine and endocrine compartments of the pancreas undergo dramatic expansion after birth and...