Vectofusin-1, a New Viral Entry Enhancer, Strongly Promotes Lentiviral Transduction of Human Hematopoietic Stem Cells

• Váldodahkkit: David Fenard (Dahkki), Dina Ingrao (Dahkki), Ababacar Seye (Dahkki), Julien Buisset (Dahkki), Sandrine Genries (Dahkki), Samia Martin (Dahkki), Antoine Kichler (Dahkki), Anne Galy (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Elsevier, 2013-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Gene transfer into hCD34+ hematopoietic stem/progenitor cells (HSCs) using human immunodeficiency virus type 1 (HIV-1)-based lentiviral vectors (LVs) has several promising therapeutic applications. Yet, efficiency, safety, and cost of LV gene therapy could be ameliorated by enhancing target cell tra...