Polysaccharide Peptide Extract From Coriolus versicolor Increased Tmax of Tamoxifen and Maintained Biochemical Serum Parameters, With No Change in the Metabolism of Tamoxifen in the Rat

• Main Authors: Valentina Razmovski-Naumovski (Author), Benjamin Kimble (Author), Daunia Laurenti (Author), Srinivas Nammi (Author), Hisayoshi Norimoto (Author), Kelvin Chan (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Polysaccharide peptide (PSP) extract of Coriolus versicolor (L.) Quél. (1886) (Trametes; Polyporaceae) is increasingly used in cancer to support the immune system. However, its interaction with tamoxifen is unknown.Aim of the study: To investigate the effect of a PSP extract on the pharm...