Relationship between Body Composition and Serum Immunoglobulin Concentrations after Administration of Intravenous Immune Globulin-Preclinical and Clinical Evidence

• Main Authors: Luigi Brunetti (Author), Helene Chapy (Author), Ronald G. Nahass (Author), Rebecca Moore (Author), Andrew Wassef (Author), Derek Adler (Author), Edward Yurkow (Author), Leonid Kagan (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this study was to investigate the effect of obesity on immunoglobulin G (IgG) pharmacokinetics in a rat model of obesity, and to collect clinical evidence for an association between the body composition and intravenous immune globulin (IVIG) pharmacokinetic parameters in humans. In a...