Synthesis, Characterization and Antibacterial Studies of 2-azetidinones Compounds Derived from Amoxicillin
In this study, the new azetidinones were synthesized from Schiff bases 2(a-j) that derived from amoxicillin (1) on treatment with chloroacetyl chloride in presence of triethylamine gave azetidinone 3(a-j). The structure of these compounds have been elucidated on the basis of their physical and spect...
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| Main Authors: | , , |
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| Format: | Book |
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College of Pharmacy / Mustansiriyah University,
2015-06-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | In this study, the new azetidinones were synthesized from Schiff bases 2(a-j) that derived from amoxicillin (1) on treatment with chloroacetyl chloride in presence of triethylamine gave azetidinone 3(a-j). The structure of these compounds have been elucidated on the basis of their physical and spectral. Azetidinone compounds were also screened for their antibacterial activity against some bacterial species using amoxicillin as standard. |
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| Item Description: | 10.32947/ajps.v15i1.160 1815-0993 2959-183X |