Acute, subacute oral toxicity and Ames test of Py-mulin: an antibacterial drug candidate

• Main Authors: Yuan Fan (Author), Yunxing Fu (Author), Yuhang Zhou (Author), Yu Liu (Author), Baocheng Hao (Author), Ruofeng Shang (Author)
• Format: Book
• Published: BMC, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Py-mulin is a new pleuromutilin derivative with potent antibacterial activities in vitro and in vivo, suggesting this compound may lead to a promising antibacterial drug after further development. The present study is aimed to evaluate the acute and subacute oral toxicity, and th...