Epigenetic Control of Haematopoietic Stem Cell Aging and Its Clinical Implications
Aging, chronic inflammation, and environmental insults play an important role in a number of disease processes through alterations of the epigenome. In this review we explore how age-related changes in the epigenetic landscape can affect heterogeneity within the haematopoietic stem cell (HSC) compar...
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| Main Authors: | , |
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| Format: | Book |
| Published: |
Hindawi Limited,
2016-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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| Summary: | Aging, chronic inflammation, and environmental insults play an important role in a number of disease processes through alterations of the epigenome. In this review we explore how age-related changes in the epigenetic landscape can affect heterogeneity within the haematopoietic stem cell (HSC) compartment and the deriving clinical implications. |
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| Item Description: | 1687-966X 1687-9678 10.1155/2016/5797521 |