Acetylsalicylic acid reduces cigarette smoke withdrawal-induced anxiety in rats via modulating the expression of NFĸB, GLT-1, and xCT

• Main Authors: Alaa M. Hammad (Author), Lujain F. Alzaghari (Author), Malek Alfaraj (Author), Walid Al-Qerem (Author), Wamidh H. Talib (Author), Fawaz Alasmari (Author), Haneen Amawi (Author), F. Scott Hall (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Chronic exposure to cigarette smoke produces neuroinflammation and long-term changes in neurotransmitter systems, especially glutamatergic systems.Objective: We examined the effects of cigarette smoke on astroglial glutamate transporters as well as NF-κB expression in mesocorticolimbic b...