Transforming Growth Factor-Beta (TGF-β) Signaling in Cancer-A Betrayal Within

• Main Authors: Abdul Basit Baba (Author), Bilal Rah (Author), Gh. Rasool Bhat (Author), Ifra Mushtaq (Author), Sabra Parveen (Author), Rukhsana Hassan (Author), Mahrukh Hameed Zargar (Author), Dil Afroze (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A ubiquitously expressed cytokine, transforming growth factor-beta (TGF-β) plays a significant role in various ongoing cellular mechanisms. The gain or loss-of-function of TGF-β and its downstream mediators could lead to a plethora of diseases includes tumorigenesis. Specifically, at the early onset...