INTERFERON BETA IN TREATMENT OF DISSEMINATED SCLEROSIS IN ADOLESCENTS - INFLUENCE ON NEUROPSYCHOLOGICAL STATUS AND PAROXYSMAL STATES
<em>Disseminated sclerosis is chronic progressive disease of central nervous system, which is characterized by demyelination, degeneration of nerve fibers and polymorphous clinical symptoms. According to literature data, 2-10% of patients have onset of a disease in childhood and adolescence. F...
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| Format: | Book |
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"Paediatrician" Publishers LLC,
2010-01-01T00:00:00Z.
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| Summary: | <em>Disseminated sclerosis is chronic progressive disease of central nervous system, which is characterized by demyelination, degeneration of nerve fibers and polymorphous clinical symptoms. According to literature data, 2-10% of patients have onset of a disease in childhood and adolescence. Frequent clinical symptoms of disseminated sclerosis, especially in adolescents, are paroxysmal states and neuropsychological disorders. Drugs containing interferon beta which are used for immunomodulating treatment, can increase the rate of paroxysmal neuropsychological disorders in patients with disseminated sclerosis. Present study with participation of 78 adolescents analyzed frequency and spectrum of neuropsychological disorders and paroxysmal states in patients 12-17 years old and relation of revealed disorders with a treatment with interferon beta.</em><br /><strong><em>Key words: adolescents, disseminated sclerosis, interferon beta, treatment, depression, paroxysmal states, anxiety, neuropsychological testing.</em></strong><br /><span style="text-decoration: underline;"><em>(<em><em>Voprosy sovremennoi pediatrii - </em></em>Current Pediatrics. - 2010;9(4):<em>34-39</em>)</em></span> |
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| Item Description: | 1682-5527 1682-5535 |