Peritoneal dialysis catheter dysfunction due to fibrin clots following treatment with tranexamic acid: a clinical case

Chronic kidney disease patients experience not only more frequent arterial and venous thrombosis but also hemorrhagic episodes. Tranexamic acid is an anti-fibrinolytic molecule that inhibits plasmin activation. It is used in hemorrhage cases (post-traumatic, gynecologic, or gastrointestinal bleeding...

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Main Authors: Elodie Bogner (Author), Elodie Ferrero (Author), Joelle Marin (Author), Stanislas Bataille (Author)
Format: Book
Published: RDPLF, 2021-05-01T00:00:00Z.
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001 doaj_e4f75cbcaade4be1aef5bac75b4e1cc7
042 |a dc 
100 1 0 |a Elodie Bogner  |e author 
700 1 0 |a Elodie Ferrero  |e author 
700 1 0 |a Joelle Marin  |e author 
700 1 0 |a Stanislas Bataille  |e author 
245 0 0 |a Peritoneal dialysis catheter dysfunction due to fibrin clots following treatment with tranexamic acid: a clinical case 
260 |b RDPLF,   |c 2021-05-01T00:00:00Z. 
500 |a 10.25796/bdd.v4i2.61393 
500 |a 2607-9917 
520 |a Chronic kidney disease patients experience not only more frequent arterial and venous thrombosis but also hemorrhagic episodes. Tranexamic acid is an anti-fibrinolytic molecule that inhibits plasmin activation. It is used in hemorrhage cases (post-traumatic, gynecologic, or gastrointestinal bleeding). We report on an original case of tranexamic acid (Exacyl®) use in a peritoneal dialysis patient for gastrointestinal bleeding of unknown origin. The use of tranexamic acid led to the Tenckhoff catheter dysfunction because of fibrin clots in the dialysate. The emergence of fibrin clots a few days after the start of tranexamic acid treatment, which never occurred again after the end of the treatment, and the anti-fibrinolytic function of tranexamic acid favors this treatment's role in fibrin clot occurrence. 
546 |a EN 
546 |a FR 
690 |a peritoneal dialysis 
690 |a tranexamic acid 
690 |a fibrin 
690 |a gastrointestinal bleeding 
690 |a clot 
690 |a fibrin clot 
690 |a Internal medicine 
690 |a RC31-1245 
655 7 |a article  |2 local 
786 0 |n Bulletin de la Dialyse à Domicile, Vol 4, Iss 2 (2021) 
787 0 |n https://www.revue-emulations.net/index.php/bdd/article/view/61393 
787 0 |n https://doaj.org/toc/2607-9917 
856 4 1 |u https://doaj.org/article/e4f75cbcaade4be1aef5bac75b4e1cc7  |z Connect to this object online.