UHPLC-Orbitrap screening of oleraindoles in hydromethanolic extracts of Portulaca oleracea

Purslane (Portulaca oleracea L., Portulacaceae) is a widespread edible plant with significant ethnobotanical and ethnopharmacological importance. The plant is characteristic for the presence of a class of indoline amide glucoside alkaloids, called cyclo-dopa amides, or oleraceins. Additionally, a ne...

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Main Authors: Yulian Voynikov (Author), Reneta Gevrenova (Author), Dimitrina Zheleva-Dimitrova (Author), Vessela Balabanova (Author), Irina Nikolova (Author), Lyubomir Marinov (Author), Iossif Benbassat (Author), Georgi Momekov (Author)
Format: Book
Published: Pensoft Publishers, 2023-12-01T00:00:00Z.
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Summary:Purslane (Portulaca oleracea L., Portulacaceae) is a widespread edible plant with significant ethnobotanical and ethnopharmacological importance. The plant is characteristic for the presence of a class of indoline amide glucoside alkaloids, called cyclo-dopa amides, or oleraceins. Additionally, a new, structurally similar to oleraceins, class of indole amides have been discovered recently, called oleraindoles. These compounds have been evaluated to possess antiinflammatory and anticholinesterase activities. Herein, utilizing UHPLC-Orbitrap-MS with MS2 filtering by diagnostic ion filtering (DIF), and diagnostic difference filtering (DDF) using different data analysis tools, eight compounds with oleraindole structure were tentatively identified.
Item Description:10.3897/pharmacia.70.e113577
2603-557X