The TKI Era in Chronic Leukemias

• Main Authors: Danilo De Novellis (Author), Fabiana Cacace (Author), Valeria Caprioli (Author), William G. Wierda (Author), Kris M. Mahadeo (Author), Francesco Paolo Tambaro (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tyrosine kinases are proteins involved in physiological cell functions including proliferation, differentiation, and survival. However, the dysregulation of tyrosine kinase pathways occurs in malignancy, including hematological leukemias such as chronic myeloid leukemia (CML) and chronic lymphocytic...