Cover Image

Targeted exon skipping of NF1 exon 17 as a therapeutic for neurofibromatosis type I

We investigated the feasibility of utilizing an exon-skipping approach as a genotype-dependent therapeutic for neurofibromatosis type 1 (NF1) by determining which NF1 exons might be skipped while maintaining neurofibromin protein expression and GTPase activating protein (GAP)-related domain (GRD) fu...

Full description

Saved in:
Bibliographic Details
Main Authors: André Leier (Author), Marc Moore (Author), Hui Liu (Author), Michael Daniel (Author), Alexis M. Hyde (Author), Ludwine Messiaen (Author), Bruce R. Korf (Author), Jamuna Selvakumaran (Author), Lukasz Ciszewski (Author), Laura Lambert (Author), Jeremy Foote (Author), Margaret R. Wallace (Author), Robert A. Kesterson (Author), George Dickson (Author), Linda Popplewell (Author), Deeann Wallis (Author)
Format: Book
Published: Elsevier, 2022-06-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items