Th17/1 and ex-Th17 cells are detected in patients with polyarticular juvenile arthritis and increase following treatment

• Main Authors: Stephanie Wood (Author), Justin Branch (Author), Priscilla Vasquez (Author), Marietta M. DeGuzman (Author), Amanda Brown (Author), Anna Carmela Sagcal-Gironella (Author), Saimun Singla (Author), Andrea Ramirez (Author), Tiphanie P. Vogel (Author)
• Format: Bog
• Udgivet: BMC, 2024-03-01T00:00:00Z.
• Fag: article
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Abstract Background A better understanding of the pathogenesis of polyarticular juvenile idiopathic arthritis (polyJIA) is needed to aide in the development of data-driven approaches to guide selection between therapeutic options. One inflammatory pathway of interest is JAK-STAT signaling. STAT3 is...