Th17/1 and ex-Th17 cells are detected in patients with polyarticular juvenile arthritis and increase following treatment

• Hauptverfasser: Stephanie Wood (Verfasst von), Justin Branch (Verfasst von), Priscilla Vasquez (Verfasst von), Marietta M. DeGuzman (Verfasst von), Amanda Brown (Verfasst von), Anna Carmela Sagcal-Gironella (Verfasst von), Saimun Singla (Verfasst von), Andrea Ramirez (Verfasst von), Tiphanie P. Vogel (Verfasst von)
• Format: Buch
• Veröffentlicht: BMC, 2024-03-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Abstract Background A better understanding of the pathogenesis of polyarticular juvenile idiopathic arthritis (polyJIA) is needed to aide in the development of data-driven approaches to guide selection between therapeutic options. One inflammatory pathway of interest is JAK-STAT signaling. STAT3 is...