TRPV1 Gates Tissue Access and Sustains Pathogenicity in Autoimmune Encephalitis

• Main Authors: Geoffrey Paltser (Author), Xue Jun Liu (Author), Jason Yantha (Author), Shawn Winer (Author), Hubert Tsui (Author), Ping Wu (Author), Yuko Maezawa (Author), Lindsay S. Cahill (Author), Christine L. Laliberté (Author), Sreeram V. Ramagopalan (Author), Gabriele C. DeLuca (Author), A. Dessa Sadovnick (Author), Igor Astsaturov (Author), George C. Ebers (Author), R. Mark Henkelman (Author), Michael W. Salter (Author), H.-Michael Dosch (Author)
• Format: Book
• Published: BMC, 2013-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Multiple sclerosis (MS) is a chronic progressive, demyelinating condition whose therapeutic needs are unmet, and whose pathoetiology is elusive. We report that transient receptor potential vanilloid-1 (TRPV1) expressed in a major sensory neuron subset, controls severity and progression of e...