Direct Renin Inhibitor is Better than Angiotensin II Receptor Blocker for Intrarenal Arterioles

• Huvudupphovsmän: Yohko Nagai (Författare, medförfattare), Kazushige Nakanishi (Författare, medförfattare), Nobuaki Yamanaka (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: Karger Publishers, 2016-08-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

Background/Aims: We have reported that the long-term administration of angiotensin II receptor blockers (ARBs) induced unusual proliferative changes of renal afferent arteriolar smooth muscle cells (SMCs) in rats, associated with the overproduction of renin. In this study, we examined that a direct...