In Situ Gel Formation in Microporated Skin for Enhanced Topical Delivery of Niacinamide
Although used widely in cosmetic formulations, topical delivery of niacinamide (LogP = −0.35) is unfavorable by conventional means. Poly(lactide-<i>co</i>-glycolide) (PLGA) formulations, can undergo a sol-gel transition triggered by solvent exchange, entrapping molecules and sustaining t...
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MDPI AG,
2020-05-01T00:00:00Z.
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