An Unusual Presentation of Spinal Giant Cell Glioblastoma in a 21-Year-Old Female

Primary spinal cord giant cell glioblastoma multiforme of the thoracic spinal cord is a rarely-diagnosed primary spinal cord tumor in comparison to neoplasms in intracranial locations. In this article, we highlight a young adult who was diagnosed with intramedullary giant cell glioblastoma, IDH wild...

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Bibliographic Details
Main Authors: Benjamin J. Delgado BS (Author), Leila Moosavi MD (Author), Ericka Rangel BS (Author), William Stull MD (Author), Rahul Dev Polineni MD (Author), Joseph Chen MD (Author), Everardo Cobos MD (Author)
Format: Book
Published: SAGE Publishing, 2019-08-01T00:00:00Z.
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520 |a Primary spinal cord giant cell glioblastoma multiforme of the thoracic spinal cord is a rarely-diagnosed primary spinal cord tumor in comparison to neoplasms in intracranial locations. In this article, we highlight a young adult who was diagnosed with intramedullary giant cell glioblastoma, IDH wild-type, World Health Organization grade IV/IV of the thoracic spinal cord. This case report describes the treatment approach with a postsurgical combination of radiation therapy and temozolomide, which resulted in the patient to return to her baseline of health only to later develop neurological symptoms significant for a recurrence of malignancy. In a review of the literature of described cases of primary spinal cord glioblastoma multiforme, prognosis continues to be unfavorable as current treatment options of the aggressive malignancy remain absent of a cure. 
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