High-CPAP Does Not Impede Cardiovascular Changes at Birth in Preterm Sheep

• Main Authors: Tessa Martherus (Author), Kelly J. Crossley (Author), Karyn A. Rodgers (Author), Janneke Dekker (Author), Anja Demel (Author), Alison M. Moxham (Author), Valerie A. Zahra (Author), Graeme R. Polglase (Author), Calum T. Roberts (Author), Arjan B. te Pas (Author), Stuart B. Hooper (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Continuous positive airway pressures (CPAP) used to assist preterm infants at birth are limited to 4-8 cmH2O due to concerns that high-CPAP may cause pulmonary overexpansion and adversely affect the cardiovascular system. We investigated the effects of high-CPAP on pulmonary (PBF) and cer...