EXPERIENCE OF INTRAMUSCULAR METHOTREXATE USE IN A PATIENT WITH EARLY POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS
This article presents a case of severe course of polyarticular juvenile idiopathic arthritis. Active articular syndrome, high laboratory parameters of disease activity, severe incompetence were observed in a child by the therapy initiation. Successful use of intramuscular methotrexate in the dose of...
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Union of pediatricians of Russia,
2014-03-01T00:00:00Z.
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| 100 | 1 | 0 | |a E. I. Alexeeva |e author |
| 700 | 1 | 0 | |a T. V. Sleptsova |e author |
| 700 | 1 | 0 | |a T. M. Bzarova |e author |
| 700 | 1 | 0 | |a S. I. Valieva |e author |
| 700 | 1 | 0 | |a R. V. Denisova |e author |
| 700 | 1 | 0 | |a K. B. Isaeva |e author |
| 700 | 1 | 0 | |a E. V. Mitenko |e author |
| 700 | 1 | 0 | |a E. G. Chistyakova |e author |
| 700 | 1 | 0 | |a A. M. Chomakhidze |e author |
| 700 | 1 | 0 | |a A. N. Fetisova |e author |
| 700 | 1 | 0 | |a O. L. Lomakina |e author |
| 700 | 1 | 0 | |a N. I. Taybulatov |e author |
| 245 | 0 | 0 | |a EXPERIENCE OF INTRAMUSCULAR METHOTREXATE USE IN A PATIENT WITH EARLY POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS |
| 260 | |b Union of pediatricians of Russia, |c 2014-03-01T00:00:00Z. | ||
| 500 | |a 1727-5776 | ||
| 500 | |a 2500-3089 | ||
| 500 | |a 10.15690/pf.v11i2.957 | ||
| 520 | |a This article presents a case of severe course of polyarticular juvenile idiopathic arthritis. Active articular syndrome, high laboratory parameters of disease activity, severe incompetence were observed in a child by the therapy initiation. Successful use of intramuscular methotrexate in the dose of 15 mg/m2 of body surface per week is described. Exudative articular alterations, arthralgiae, morning stiffness duration reduced as early as one month after the therapy initiation in a child. Acute inflammatory articular alterations cut off, range of motions recovered completely in 4 out of the 6 affected joints, laboratory parameters of disease activity reduced and normalized (ESR and CRP), inactive disease stage was registered after 6 months of treatment. We did not observe any undesirable phenomena in the setting of methotrexate therapy. | ||
| 546 | |a RU | ||
| 690 | |a children | ||
| 690 | |a polyarticular juvenile idiopathic arthritis | ||
| 690 | |a methotrexate | ||
| 690 | |a intramuscular administration | ||
| 690 | |a Pediatrics | ||
| 690 | |a RJ1-570 | ||
| 690 | |a Therapeutics. Pharmacology | ||
| 690 | |a RM1-950 | ||
| 655 | 7 | |a article |2 local | |
| 786 | 0 | |n Педиатрическая фармакология, Vol 11, Iss 2, Pp 48-54 (2014) | |
| 787 | 0 | |n https://www.pedpharma.ru/jour/article/view/119 | |
| 787 | 0 | |n https://doaj.org/toc/1727-5776 | |
| 787 | 0 | |n https://doaj.org/toc/2500-3089 | |
| 856 | 4 | 1 | |u https://doaj.org/article/e60f8268ef044e719c7bd5f20e00bc5d |z Connect to this object online. |