Treating Cancer by Targeting Telomeres and Telomerase

• Prif Awduron: Marko Ivancich (Awdur), Zachary Schrank (Awdur), Luke Wojdyla (Awdur), Brandon Leviskas (Awdur), Adijan Kuckovic (Awdur), Ankita Sanjali (Awdur), Neelu Puri (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2017-02-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Telomerase is expressed in more than 85% of cancer cells. Tumor cells with metastatic potential may have a high telomerase activity, allowing cells to escape from the inhibition of cell proliferation due to shortened telomeres. Human telomerase primarily consists of two main components: hTERT, a cat...