Urokinase Receptor and Resistance to Targeted Anticancer Agents
The urokinase receptor/uPAR is a GPI-anchored membrane protein, which regulates protease activity at the cell surface and, in collaboration with a system of co-receptors, triggers cell-signaling and regulates gene expression within the cell. In normal tissues, uPAR gene expression is limited; howeve...
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Frontiers Media S.A.,
2015-07-01T00:00:00Z.
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