Platinum and Taxane Based Adjuvant and Neoadjuvant Chemotherapy in Early Triple-Negative Breast Cancer: A Narrative Review

• Main Authors: Hao Tian (Author), Dandan Ma (Author), Xuanni Tan (Author), Wenting Yan (Author), Xiujuan Wu (Author), Cheng He (Author), Ling Zhong (Author), Yan Zhang (Author), Bingjie Yu (Author), Yi Zhang (Author), Xiaowei Qi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Platinum (Pt) derivatives such as cisplatin and carboplatin are the class of drugs with proven activity against triple-negative breast cancer (TNBC). This is due to the ability of Pt compounds to interfere with the DNA repair mechanisms of the neoplastic cells. Taxanes have been efficacious against...