20-hydroxyecdysone dilates muscle arterioles in a nitric oxide-dependent, estrogen ER-β receptor-independent manner

• Main Authors: Nelson N Orie (Author), Asmaa Raees (Author), Maneera Y. Aljaber (Author), Nada Mohamed-Ali (Author), Halima Bensmail (Author), Mostafa M. Hamza (Author), Nasser Al-Ansari (Author), Alka Beotra (Author), Vidya Mohamed-Ali (Author), Mohammed Almaadheed (Author)
• Format: Book
• Published: Elsevier, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: 20-hydroxyecdysone is an ecdysteroid which is abundant in plants and insects and has anabolic potentials in mammals. It was recently shown to have affinity for estrogen ER-β receptor, which could potentially make it vasodilatory. Yet this possibility has not been previously investigated....