Mitophagy and Oxidative Stress: The Role of Aging

• Main Authors: Anna De Gaetano (Author), Lara Gibellini (Author), Giada Zanini (Author), Milena Nasi (Author), Andrea Cossarizza (Author), Marcello Pinti (Author)
• Format: Book
• Published: MDPI AG, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitochondrial dysfunction is a hallmark of aging. Dysfunctional mitochondria are recognized and degraded by a selective type of macroautophagy, named mitophagy. One of the main factors contributing to aging is oxidative stress, and one of the early responses to excessive reactive oxygen species (ROS...