Efficacy Of Pimozide In Delusion Of Parasitosis

Twenty patients of dulusion of parasitosis received oral pimozide (PMZ) 2 mg daily for 3 months. Trihexyphenydyl hydrochloride (THP) was administered in a dose of 4 mg daily in young adults and 2 mg daily in elderly patients for prevention of extrapyramidal side effects (EPS). Within 1-2 week of ini...

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Bibliographic Details
Main Authors: Chakraborty Kalyan (Author), Roy Aloke Kumar (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 1998-01-01T00:00:00Z.
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Summary:Twenty patients of dulusion of parasitosis received oral pimozide (PMZ) 2 mg daily for 3 months. Trihexyphenydyl hydrochloride (THP) was administered in a dose of 4 mg daily in young adults and 2 mg daily in elderly patients for prevention of extrapyramidal side effects (EPS). Within 1-2 week of initiation of therapy, sixteen patients responded completely. In four patients, dosage of PMZ had to be increased to 4 mg daily and they responded 3-4 week after initiation of therapy. Treatment was continued for 3 months and all were symptom free. Following discontinuation of therapy, delusion reappeared but disappeared after reinstitution of PMZ therapy. EPS developed in two young patients resulting in discontinuation of pimozide.
Item Description:0019-5154
1998-3611