Re-establishing Apoptosis Competence in Bone Associated Cancers via Communicative Reprogramming Induced Through Notch Signaling Inhibition

• المؤلفون الرئيسيون: Michela Colombo (مؤلف), Natalia Platonova (مؤلف), Domenica Giannandrea (مؤلف), Maria Teresa Palano (مؤلف), Andrea Basile (مؤلف), Raffaella Chiaramonte (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2019-02-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Notch and its ligands on adjacent cells are key mediators of cellular communication during developmental choice in embryonic and adult tissues. This communication is frequently altered in the pathological interaction between cancer cells and healthy cells of the microenvironment due to the aberrant...