Possible Mechanisms Underlying Statin-Induced Skeletal Muscle Toxicity in L6 Fibroblasts and in Rats
3-Hydroxy-3-methylglutaryl CoA reductase inhibitors (statins) are safe and well-tolerated therapeutic drugs. However, they occasionally induce myotoxicity such as myopathy and rhabdomyolysis. Here, we investigated the mechanism of statin-induced myotoxicity in L6 fibroblasts and in rats in vivo. L6...
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| Main Authors: | , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2009-01-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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