Treatment with Anti-HMGB1 Monoclonal Antibody Does Not Affect Lupus Nephritis in MRL/lpr Mice
Abstract High mobility group box 1 (HMGB1) is a nuclear DNA binding protein that acts as an alarmin when secreted. HMGB1 is increased in systemic lupus erythematosus and might represent a potential therapeutic target. We investigated whether treatment with an anti-HMGB1 antibody affects the developm...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
BMC,
2016-01-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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