The chemokine CXCL1/growth related oncogene increases sodium currents and neuronal excitability in small diameter sensory neurons

• Main Authors: Wick Dayna M (Author), Coyle Dennis E (Author), Yang Rui-Hua (Author), Xie Wenrui (Author), Strong Judith A (Author), Wang Jun-Gang (Author), Dorsey Ericka D (Author), Zhang Jun-Ming (Author)
• Format: Book
• Published: SAGE Publishing, 2008-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Altered Na⁺channel expression, enhanced excitability, and spontaneous activity occur in nerve-injury and inflammatory models of pathological pain, through poorly understood mechanisms. The cytokine GRO/KC (gro...